What is placenta extract, and why is it popular in Japan?

Short answerPlacenta extract is a supplement (and skincare) ingredient valued in Japan for beauty-from-within and vitality. It contains amino acids, peptides and growth factors. In Japan, injectable placenta preparations have long been used medically, and oral placenta supplements are a popular beauty category — though evidence for the supplements is limited.

Placenta extract is one of the most distinctive ingredients in Japanese beauty supplements. Marketed for skin radiance, vitality and "beauty from within," it's far more mainstream in Japan than in many Western markets.

What to know

  • What it contains: amino acids, peptides and growth factors, depending on the source and processing.
  • Japan's context: injectable human-placenta pharmaceuticals have been approved and used in Japan for decades (e.g. for liver and menopausal support), which is part of why the ingredient is trusted there. Oral supplements are a separate, beauty-focused category.
  • Sources: supplements typically use porcine (pig), equine, or marine placenta; "plant placenta" is a different, botanical ingredient.

Evidence for oral placenta supplements is limited, so treat the beauty claims as promising rather than proven. Neoi's PCN placenta sits in our supplement range; see also is placenta safe and NMN vs placenta.

This information is educational and is not medical advice. Dietary supplements are not intended to diagnose, treat, cure or prevent any disease, and these statements have not been evaluated by the FDA. Talk to a qualified healthcare professional before starting any supplement, especially if you are pregnant, nursing, taking medication or managing a health condition.